There are five major hospitals in Norfolk alone – Sentara Norfolk General Hospital, Sentara Leigh Hospital, Children’s Hospital of King Daughters, Bon Secours Depaul Medical Center, and Eastern Virginia Hospital. These hospitals provide all medical facilities from cancer care to women’s health.

Sentara Hospital has two chains in Norfolk. Sentara Leigh specializes in orthopedic, gynecological and urological services while Sentara Norfolk General Hospital is the only hospital in Norfolk that offers Level I Trauma treatment and Special Burn Unit. Sentara Norfolk General Hospital has a 569-bed tertiary care facility. For nine straight years, the National Research Corporation has named Sentara Norfolk General Hospital Hampton Roads Consumer’s Choice award winner. Heart and Heart Surgery services at Sentara Norfolk General Hospital are listed among the top 50 cardiac programs in the nation in this year's edition of U.S. News & World Report magazine. Sentara Leigh Hospital is a 250-bed facility. Phone number for Sentara General and Sentara Leigh is 757-668-3000/3201 and 757-466-6700, respectively.

Children’s Hospital of The King’s Daughters (CHDK) is the facility of choice for pediatric care in southeastern Virginia and northeastern North Carolina. Whether a child needs hospitalization, ongoing care for a chronic illness, outpatient surgery or primary care, CHKD Health System provides the staff, facilities and technologies that address the unique demands of childhood. Since the Norfolk City Union of The King’s Daughters established the hospital in 1961, CHKD has undergone two major renovations and expansions and is now at the hub of a comprehensive system of caring dedicated exclusively to children. Phone number for CHDK is 757-688-7000

Among the hospitals in Norfolk, Eastern Virginia Hospital is perhaps the most prestigious one along with its medical school. The campus includes Sentara General Hospital and the Children’s Hospital of King Daughters. The hospital is well known for its reproductive medicine and research in cancer, pediatrics, geriatrics and diabetes. Eastern Virginia Hospital is divided into different institutions as it is also part of the medical schools - The Jones Institute for Reproductive Medicine – Opened in 1992, this building brought together in one location the 150 physicians, scientists, and staff of the Department of Obstetrics and Gynecology's renowned division of reproductive medicine and South Campus Building – Home to the Center for Pediatric Research (a joint program with Children’s Hospital of The King’s Daughters) and the Department of Internal Medicine's Division of Endocrinology and Diabetes, also known as the Leonard R. Strelitz Diabetes Institutes. The phone number for Eastern Virginia Hospital is 757-446-5227.